KMID : 0363219970350010204
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Korean Journal of Dermatology 1997 Volume.35 No. 1 p.204 ~ p.208
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Three Cases of Acquired Reactive Perforating Collagenosis
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Abstract
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Reactive perforating collagenosis (RPC) is a rare perforating disorder characterized by transepithelial elimination of altered collagen. Two types of RPC occur:inherited and acquired. The acquired type arises during adult life without a familial
tendency. It is accompanied by scratching and usually is associated with diabetes mellitus, chronic renal failure, lymphoma and AIDS.
We report three cases of the acquired form of RPC. Pruritus was the common factor among them. In two patients, chronic renal failure and hyperthyroidism were associated with RPC. Histopathological and ultrastructural findings showed
transepithelial
elimination of collagen. Control of itching was helpful for clearing the lesions. (Kor J Dermatol 1997;35(1):204¡208)
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KEYWORD
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